Universitätsklinikum Carl Gustav Carus Dresden | Germany | 01xxx Dresden | Full time | Published since: 02.02.2026 on stepstone.de
PhD Position (m/f/d) - Computational Biology & Single-Cell Genomics - Decoding Brain Development
The Functional Neurogenomics research group led by Philipp Abe investigates the molecular foundations of brain development, with a particular focus on the early formation of neural circuits. Within the framework of the “ThalamoConnect” project, state-of-the-art single-cell technologies and bioinformatic analyses are employed to decipher the genetic programs that govern the connectivity of brain regions and play a role in neurological disorders when these processes are disrupted. .
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Your tasks • Your profile • What we offer
Analysis interpretation of high-resolution single-cell RNA-seq and scATAC-seq data to elucidate cellular processes Processing and integration of spatial transcriptomics data to reveal molecular patterns in their tissue context Development, optimization, and application of bioinformatic pipelines for data integration, analysis, and visualization of complex datasets Computational modeling of gene regulatory networks to investigate molecular control mechanisms Active contribution to scientific publications and support in project and third-party funding applications with the aim of completing a doctorate (Ph.D. / Dr. rer. medic.) Supervision and technical support of students (Bachelor's, Master's, medical students) in daily laboratory and project work
Completed university degree in bioinformatics, computational biology, statistics, or a comparable field Strong programming skills in common analysis environments search as R and/or Python Experience in the analysis of single-cell genomics data, ideally using tools such as Seurat or Scanpy Enthusiasm for statistical modeling and machine learning to analyze complex biological datasets High level of care and attention to detail Excellent teamwork and communication skills Initiative and strong self-organization skills
at the Institute of Clinical Genetics The doctoral position is available as soon as possible and is initially limited to a period of three years. Remuneration is based on the pay scale regulations of the Collective Agreement for the Public Service of the Federal States (TV-L) and, subject to personal eligibility, is possible at pay group E13 (65% doctoral position). Convincing Across the Board: A stimulating research environment at a leading university medical center Access to TUD High-Performance Computing resources Close supervision and integration into collaborative research networks Compensation: In accordance with the collective agreement, plus an annual special payment, subject to personal eligibility Leave: 30 days of paid annual leave Professional Development: Extensive internal and external training and continuing training opportunities to strengthen your skills Work Culture: We value transparency, team spirit, and shared success. Join us activities at social events or sporting search as the REWE Team Challenge Mobility: Job bike program and grant for public tickets to support an environmental friendly and convenient commute Health & Well-being: Access to modern sports and exercise programs at our health center, mental health initiatives, and comprehensive occupational health management Employee Benefits: Discounts at our hospital pharmacy, exclusive corporate benefits, and additional shopping platforms
Location
![]() | Universitätsklinikum Carl Gustav Carus Dresden | |
| 01307 Dresden | ||
| Germany |
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