PhD position - Functional and molecular characterization of AI-based morphological predictors of Ven/Aza therapy response in AML (m/f/d)

Branche: Gesundheits- und Krankenpfl... Branche: Gesundheits- und Krankenpflege, Rettungsdienst und Geburtshilfe

The University Hospital Heidelberg is one of the major healthcare centers in Germany. Our objective is the development of innovative diagnostics and therapies as well as their quick implementation for the patient. With about 14,000 employees in more than 50 specialized clinical departments with almost 2,500 beds, about 80,000 patients in part-time and full-time inpatient treatment as well as 1,000,000 patients in ambulant treatment are medicated each year.

PhD position - Functional and molecular characterization of AI-based morphological predictors of Ven/Aza therapy response in AML (m/f/d)

wanted for the next possible date at the Department of Medicine V, Hematology, Oncology, Rheumatology.

For our project “Functional and molecular characterization of AI-based morphological predictors of therapy response in Acute Myeloid Leukemia“ we are looking for a PhD student. The project is is part of the SFB/CRC 1709 “Cellular Plasticity in Myeloid Malignancies: From Mechanisms to Therapies-. In this CRC we will focus on myeloid malignancies as a model to dissect the various molecular mechanisms that enable and regulate cancer cell plasticity in AML. Our overall goal is to pave the way for new cancer therapies.

The aim of this PhD position is to perform and to functionally and molecularly characterize multiomics single cell sequencing datasets and to combine these data with AI analyses from bone marrow smears. We aim to analyze mechanisms and also to develop new biomarkers for therapy response and resistance.

• Job-ID: V000014467
• Field of application: Klinik für Hämatologie, Onkologie und Rheumatologie
• Location: Heidelberg
• Start date: as of now
• Job Category: Science and teaching
• Working hours: Part time (65 %)
• Limitation: Temporary (2 Jahre, Verlängerung angestrebt)
• Contract: TV-L