Post-Doc – Freez-Thaw Studies on Biologics (all genders) (full-time, temporary for 24 months)

Branche: Pharmazie Branche: Pharmazie

Welcome to AbbVie! As part of an international company with 50,000 employees worldwide and around 3,000 employees in Germany, you will have the opportunity of addressing some of tomorrows unmet medical needs in close collaboration with your colleagues. Are you passionate about improving global health care? Do you want to contribute to improving patients' quality of life through your expertise? In a challenging work environment that offers opportunities of developing and increasing your own skills? You've come to the right place!

In our Pharmaceutical development department within Product Development Science & Technology (PD S&T) at the Ludwigshafen site, you will be working in a team of talented people and experienced experts toward developing tomorrow's products. In cutting-edge laboratories, you will be setting the highest standards in the competitive field.

Moving mountains together – as

Post-Doc – Freez-Thaw Studies on Biologics (all genders) (full-time, temporary for 24 months)

Product Development, Science and Technology (PDS&T) drives product development of assets which proved effective in early clinical trials and provides support for on-market products. Biologics drug substances are typically stored as frozen solutions prior to drug product manufacturing. The thawing and freezing of these solutions, particularly repeated cycles, are known to bear the risk of protein damage. Based on current knowledge of the mechanisms of freeze-thaw instability, you design, conduct and evaluate studies pushing for a deeper understanding of the dynamic mechanism in relevant formulations and publish results in peer-reviewed journals. A substantial arm of the studies will be evaluations on the influence of excipient crystallization on freeze-thaw instability.